Some types of data sources are not supported for ArcGIS Runtime. You have referenced one of these data sources in your document.
Solution
- Replace the unsupported data source with a supported geodatabase feature class. The following table lists unsupported data sources and suggested alternatives:Unsupported data sources Suggested alternatives ArcInfo coverage Convert the data to feature classes in a geodatabase. CAD Import CAD content into a geodatabase feature class. Excel file Generate features for each Excel spreadsheet and load the resulting feature classes into a geodatabase feature class. ArcIMS feature service Load the original data source into a geodatabase feature class. In-memory feature class Save in-memory data as a feature class in a geodatabase. ArcGIS feature service Convert the data to feature classes in a geodatabase. PC ARC/INFO coverage Convert your PC ARC/INFO coverages into geodatabase feature classes. Unsupported data sources for ArcGIS Runtime 
- Alternatively, if you do not need the map layer that has an unsupported data source in your basemap layer or map service, you can delete the map layer from your ArcMap document.