File geodatabases provide a convenient method for data storage that can be used with both ArcGIS Server sites on Amazon Web Services (AWS). The file geodatabases should be placed or created on an Elastic Block Store (EBS) of your ArcGIS Enterprise on Amazon Web Services instances so they can be moved between instances more easily.
To help you decide whether you want to use a file geodatabase to store your data for use with your ArcGIS Server on AWS, see Data storage considerations for an ArcGIS Server site.